| Indicatie: | |
| Studie: | HO165 |
| Phase 2 study of venetoclax treatment (26 cycles) with 6 cycles or 26 cycles of epcoritamab in patients with relapsed or refractory chronic lymphocytic leukemia or Small Lymphocytic Lymphoma (AETHER). |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | |
| Studie: | HO170 |
| ANTICIPATE: Prevention of ANThracycline-Induced Cardiac dysfunction by dexrazoxane In PATients with diffusE large B-cell lymphoma: a phase III national multicenter prospective randomized open-label trial |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | ≥ 18 jr, niet fit |
| Studie: | HO177 |
| Randomized study assessing azacitidine and venetoclax with or without revumenib in adult patients with newly diagnosed NPM1 mutated or KMT2A rearranged AML ineligible for intensive chemotherapy |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | ≥ 18 jr, niet fit |
| Studie: | HO173 |
| Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | Previously Untreated Follicular Lymphoma |
| Studie: | M22-003 (AbbVie) Epcorita |
| M22-003: A Phase 3, Multicenter, Randomized, Open-Label Trial to Evaluate the Safety and Efficacy of Epcoritamab + Rituximab and Lenalidomide (R2) compared to Chemoimmunotherapy in Previously Untreated Follicular Lymphoma (EPCOREFL-2) |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | >18 years old, diagnosed with MM |
| Studie: | Hovon 174 - FABULOUS |
| FeAsiBility of a treatment free interval in newly diagnosed mUltiple myeLOma patients treated with DaratumUmab-Lenalidomide-DexamethaSone the FABULOUS study |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | OPEN |
|
| Indicatie: | Patients with newly diagnosed AML who are not considered candidates for intensive treatment regimens |
| Studie: | Hovon 171 |
| A single arm phase II trial to assess cobicistat boosted venetoclax in combination with azacitidine (sc) in patients with newly diagnosed acute myeloid leukaemia (AML) who are not considered candidates for intensive treatment regimens |
| Open in: | HAGA
LUMC |
| Contact: | researchhematologie@hagaziekenhuis.nl; P.A.von_dem_Borne@lumc.nl |
| Status: | OPEN |
|
| Indicatie: | Adult (≥18 years old) participants with primary ITP who had an insufficient response to or relapsed after first-line treatment with corticosteroids ±IVIG, and who have a platelet count below 30 G/L, for whom eltrombopag is clinically indicated as per physicians discretion and with no contraindication to receive eltrombopag. |
| Studie: | VAYHIT2 |
| A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) |
| Open in: | LUMC |
| Contact: | j.j.zwaginga@lumc.nl |
| Status: | CLOSED |
|
| Indicatie: | Adult patients with relapsed or refractory HLA-A*02:01-positive NPM1-
mutated AML.
|
| Studie: | LUMC NPM1-TCR studie |
| A phase I/II trial of MB-dNPM1-TCR.1 in HLA-A*02:01-positive patients with relapsed or
refractory NPM1-mutated AML to determine safety and obtain first data on efficacy
|
| Open in: | LUMC |
| Contact: | C.J.M.Halkes@lumc.nl |
| Status: | OPEN |
|
| Indicatie: | Patients ≥ 18 years of age with previously untreated CLL in need of treatment |
| Studie: | BGB 11417-301 |
| A Phase 3, Open-Label, Randomized Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Patients With Previously Untreated Chronic Lymphocytic Leukemia |
| Open in: | HAGA |
| Contact: | researchhematologie@hagaziekenhuis.nl |
| Status: | CLOSED |
|